<?xml version='1.0' encoding='UTF-8'?><rss xmlns:atom='http://www.w3.org/2005/Atom' xmlns:openSearch='http://a9.com/-/spec/opensearchrss/1.0/' version='2.0'><channel><atom:id>tag:blogger.com,1999:blog-4472611192504114204</atom:id><lastBuildDate>Wed, 20 Feb 2008 12:26:08 +0000</lastBuildDate><title>Suboxone Talk Zone</title><description/><link>http://subox.info/blog.html</link><managingEditor>Jeffrey Junig</managingEditor><generator>Blogger</generator><openSearch:totalResults>9</openSearch:totalResults><openSearch:startIndex>1</openSearch:startIndex><openSearch:itemsPerPage>25</openSearch:itemsPerPage><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-2400548468433875513</guid><pubDate>Mon, 04 Feb 2008 14:31:00 +0000</pubDate><atom:updated>2008-02-04T11:04:06.624-08:00</atom:updated><title>I'm not like those people...</title><description>A recent letter and response that addresses the 'terminal uniqueness' issue:&lt;br /&gt;&lt;br /&gt;&lt;span style="font-family:'Tahoma','sans-serif';font-size:12;"&gt;Hi and thx for getting back to me. I have never tried anything to get off of these pills. I am not your stereotypical addict. Truth be told I have never been addicted in my life. I feel like such a loser for letting myself get out of control and if it was not for being sick I would have licked this a long time ago! I am not off them right now because I cant. I work hard all day to support my family and there is no time to be down and out. I have also suffered an incredible string of losses over the past two years. What a predicament huh? I lost my wife two years ago, and the story goes on. I have chronic back pain from degenerative discs, but I will deal with that. Will suboxone do anything for me?&lt;br /&gt;&lt;br /&gt;My response:&lt;br /&gt;&lt;br /&gt;&lt;/span&gt;&lt;p class="MsoNormal"&gt;&lt;span style="COLOR: rgb(31,73,125);font-family:'Calibri','sans-serif';font-size:12;"  &gt;I have a couple things to say that may come across as ‘brutally honest’—don’t take it personally, but rather understand that EVERY person who gets stuck on opiates has a unique story, and we all were reluctant to see ourselves as ‘stereotypical addicts’. There is a term in addiction—‘terminal uniqueness’—that refers to a state of mind that is common with addiction, and which keeps people sick. A frequent refrain by a person new to a treatment center is ‘I’m not like those people’. The fact of the matter is that one rarely sees a ‘stereotypical addict’ at treatment. What one sees are teachers, dentists, single and married moms, college students, high school students, people with back problems or fibromyalgia, people who have been through terrible tragedies… So try to avoid seeing the things that make you unique. Instead, try to see the things that make you like everyone else—the horrible feeling of being trapped by something, when you have always handled things well up until now. That is how most people who are stuck on opiates feel—trapped, embarrassed, ashamed, angry… and afraid. Others don’t feel anything because they repress all of their feelings and put up a fake, cocky exterior. That is what denial is all about.&lt;?xml:namespace prefix = o /&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;As an aside, I own the domain name 'terminaluniqueness.com'-- I will be advertising a book through there eventually... I hope.... But if you search under 'terminal uniqueness' you will find a number of things written by recovering people.&lt;br /&gt;&lt;br /&gt;J</description><link>http://subox.info/2008/02/im-not-like-those-people.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-6299458511609168765</guid><pubDate>Sun, 03 Feb 2008 03:39:00 +0000</pubDate><atom:updated>2008-02-02T19:51:54.646-08:00</atom:updated><title>Is Suboxone At Odds With Traditional Recovery?</title><description>&lt;p class="MsoNormal" style="margin-left: 1.5in; text-align: center; text-indent: 0.5in;" align="center"&gt;&lt;b style=""&gt;&lt;span style=";font-size:10;color:black;"  &gt;&lt;span style=""&gt;                                                                     &lt;/span&gt;Jeffrey T Junig MD PhD&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/b&gt;&lt;/p&gt;      &lt;p class="MsoNormal"&gt;&lt;b style=""&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/b&gt;&lt;span style="color:black;"&gt;By now almost every opiate addict has heard of suboxone, the amazing medication for opiate dependence that has taken the using world by storm.&lt;span style=""&gt;  &lt;/span&gt;I will admit to mixed feelings about suboxone based on what I have seen and heard while treating well over 100 patients over the past two years.  I also acknowledge that my opinions are likely influenced by my own experiences as an addict in traditional recovery.&lt;span style=""&gt;  &lt;/span&gt;While suboxone has opened a new frontier of treatment for opiate addiction, it also threatens to split the recovering and treatment communities along opposing battle lines.&lt;span style=""&gt;  &lt;/span&gt;Such and outcome would be a huge missed opportunity to improve the lives of opiate addicts. &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;An amazing medication.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt; &lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;span style="color:black;"&gt;For clarification, the active ingredient in Suboxone is buprenorphine, a partial agonist at the mu opiate receptor. Suboxone contains naloxone to prevent intravenous use; another form of the medication, Subutex, consists of buprenorphine without naloxone.&lt;span style=""&gt;  &lt;/span&gt;In this article I will use the name ‘Suboxone’ because of the common reference to the drug, but in all cases I am referring to the use and actions of buprenorphine in either form.&lt;span style=""&gt;  &lt;/span&gt;The unique effects of buprenorphine can be attributed to the drug’s unique molecular properties.&lt;span style=""&gt;  &lt;/span&gt;First, the partial agonist effect at the receptor level results in a ‘ceiling effect’ to dosing after about 4 mg, so that increased dosing does not result in increased opiate effect beyond that dose.&lt;span style=""&gt;  &lt;/span&gt;Second, the high binding affinity and partial agonist effect cause the elimination of drug cravings, dispelling the destructive obsession with use that destroys the personality of the user.&lt;span style=""&gt;  &lt;/span&gt;Third, the high protein binding and long half-life of buprenorphine allows once per day dosing, allowing the addict to break the conditioned pattern of withdrawal (stimulus)-use (response)- relief (reward) which is the backbone of addictive behavior.&lt;span style=""&gt;  &lt;/span&gt;Fourth, the partial agonist effect and long half life cause rapid tolerance to the drug, allowing the patient to feel ‘normal’ within a few days of starting treatment.&lt;span style=""&gt;  &lt;/span&gt;Finally, the withdrawal from buprenorphine provides a disincentive to stop taking the drug, and so the drug is always there to assure the person that any attempt to get high would be futile, dispelling any lingering thoughts about using an opiate.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;Different treatment approaches.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt; &lt;/o:p&gt;At the present time there are significant differences between the treatment approaches of those who use suboxone versus those who use a non-medicated 12-step-based approach.  People who stay sober with the help of AA, NA, or CA, as well as those who treat by this approach tend to look down on patients taking suboxone as having an ’inferior’ form of recovery, or no recovery at all.  This leaves suboxone patients to go to Narcotics Anonymous and hide their use of suboxone.  On one hand, good boundaries include the right to keeping one’s private medical information so one’s self.  But on the other hand, a general recovery principle is that ’secrets keep us sick’, and hiding the use of suboxone is a bit at odds with the idea of ’rigorous honesty’. People new to recovery also struggle with low self esteem before they learn to overcome the shame society places on ‘drug addicts’;&lt;span style=""&gt;  &lt;/span&gt;they are not in a good position to deal with even more shame coming from other addicts themselves! &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;/span&gt;&lt;span style="color:black;"&gt;An ideal program will combine the benefits of 12-step programs with the benefits of the use of suboxone.&lt;span style=""&gt;  &lt;/span&gt;The time for such an approach is at hand, as it is likely that more and more medications will be brought forward for treatment of addiction now that suboxone has proved profitable.  If we already had excellent treatments for opiate addiction there would be less need for the two treatment approaches to learn to live with each other.&lt;span style=""&gt;  &lt;/span&gt;But the sad fact is that opiate addiction remains stubbornly difficult to treat by traditional methods.&lt;span style=""&gt;  &lt;/span&gt;Success rates for long-term sobriety are lower for opiates than for other substances.&lt;span style=""&gt;  &lt;/span&gt;This may be because the ‘high’ from opiate use is different from the effects of other substances—users of cocaine, methamphetamine, and alcohol take the substances to feel up, loose, or energetic—ready to go out and take on the town.&lt;span style=""&gt;  &lt;/span&gt;The ‘high’ of opiate use feels content and ‘normal’— users feel at home, as if they are getting back a part of themselves that was always missing. The experience of using rapidly becomes a part of who the person IS, rather than something the patient DOES.&lt;span style=""&gt;  &lt;/span&gt;The term ‘denial’ fits nobody better than the active opiate user, particularly when seen as the mnemonic:&lt;span style=""&gt;  &lt;/span&gt;Don’t Even Notice I Am Lying.&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;        &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;The challenges for practitioners lie at the juncture between traditional recovery and the use of medication, in finding ways to bring the recovering community together to use all available tools in the struggle against active opiate addiction.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;Drug obsession and character defects.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;&lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;Suboxone has given us a new paradigm for treatment which I refer to as the ‘remission model’.  This model takes into account that addiction is a dynamic process— far more dynamic than previously assumed.  To explain, the traditional view from recovery circles is that the addict has a number of character defects that were either present before the addiction started, or that grew out of addictive behavior over time.&lt;span style=""&gt;  &lt;/span&gt;Opiate addicts have a number of such ‘defects.’&lt;span style=""&gt;  &lt;/span&gt;The dishonesty that occurs during active opiate addiction, for example, far surpasses similar defects from other substances, in my opinion.&lt;span style=""&gt;  &lt;/span&gt;Other defects are common to all substance users; the addict represses awareness of his/her trapped condition and creates an artificial ‘self’ that comes off as cocky and self-assured, when deep inside the addict is frightened and lonely.&lt;span style=""&gt;  &lt;/span&gt;The obsession with using takes more and more energy and time, pushing aside interests in family, self-care, and career.&lt;span style=""&gt;  &lt;/span&gt;The addict becomes more and more self-centered, and the opiate addict often becomes very ‘somatic’, convinced that every uncomfortable feeling is an unbearable component of withdrawal.&lt;span style=""&gt;  &lt;/span&gt;The opiate addict becomes obsessed with comfort, avoiding activities that cause one to perspire or exert one’s self.&lt;span style=""&gt;  &lt;/span&gt;The active addict learns to blame others for his/her own misery, and eventually their irritability results in loss of jobs and relationships.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;The traditional view holds that these character defects do not simply go away when the addict stops using.&lt;span style=""&gt;  &lt;/span&gt;People in AA know that simply remaining sober will cause a ‘dry drunk’—a nondrinker with all of the alcoholic character defects-- when there is no active recovery program in place.&lt;span style=""&gt;  &lt;/span&gt;I had such an expectation when I first began treating opiate addicts with suboxone—that without involvement in a 12-step group the person would remain just as miserable and dishonest as the active user.&lt;span style=""&gt;  &lt;/span&gt;I realize now that I was making the assumption that character defects were relatively static—that they developed slowly over time, and so could only be removed through a great deal of time and hard work.&lt;span style=""&gt;  &lt;/span&gt;The most surprising part of my experience in treating people with suboxone has been that the defects in fact are not ‘static’, but rather they are quite dynamic.&lt;span style=""&gt;  &lt;/span&gt;I have come to believe that the difference between suboxone treatment and a patient in a ‘dry drunk’ is that the suboxone-treated patient has been freed from the obsession to use.&lt;span style=""&gt;  &lt;/span&gt;A patient in a ‘dry drunk’ is not drinking, but in the absence of a recovery program they continue to suffer the conscious and unconscious obsession with drinking.&lt;span style=""&gt;   &lt;/span&gt;People in AA will often say that it isn’t the alcohol that is the problem; it is the ‘ism’ that causes the damage.&lt;span style=""&gt;  &lt;/span&gt;Such is the case with opiates as well—the opiate is not the issue, but rather it is the obsession with opiates that causes the misery and despair.&lt;span style=""&gt;  &lt;/span&gt;With this in mind, I now view character defects as features that develop in response to the obsession to use a substance.&lt;span style=""&gt;  &lt;/span&gt;When the obsession is removed the character defects will go way, whether slowly, through working the 12 steps, or rapidly, by the remission of addiction with suboxone.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;In traditional step-based treatment the addict is in a constant battle with the obsession to use. Some addicts will have rapid relief from their obsession when they suddenly experience a ‘shift of thinking’ that allows them to see their powerlessness with their drug of choice. &lt;span style=""&gt;  &lt;/span&gt;For other addicts the new thought requires a great deal of addition-induced misery before their mind opens in response to a ‘rock bottom’. But whether fast or slow, the shift of thinking is effective because the new thought approaches addiction where it lives—in the brain’s limbic system.&lt;span style=""&gt;  &lt;/span&gt;The ineffectiveness of higher-order thinking has been proven by addicts many times over, as they make promises over pictures of their loved ones or try to summon the will power to stay clean.&lt;span style=""&gt;  &lt;/span&gt;While these approaches almost always fail, the addict will find success in surrender and recognition of the futility of the struggle.&lt;span style=""&gt;  &lt;/span&gt;The successful addict will view the substance with fear—a primitive emotion from the old brain. &lt;span style=""&gt; &lt;/span&gt;When the substance is viewed as a poison that will always lead to misery and death, the obsession to use will be lifted.&lt;span style=""&gt;  &lt;/span&gt;Unfortunately it is man’s nature to strive for power, and over time the recognition of powerlessness will fade.&lt;span style=""&gt;  &lt;/span&gt;For that reason, addicts must continue to attend meetings where newcomers arrive with stories of misery and pain, which reinforce and remind addicts of their powerlessness.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;The dynamic nature of personality.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;My experiences with Suboxone have challenged my old perceptions, and led me to believe that the character defects of addiction are much more dynamic.&lt;span style=""&gt;  &lt;/span&gt;Suboxone removes the obsession to use almost immediately.&lt;span style=""&gt;  &lt;/span&gt;The addict does not then enter into a ‘dry drunk’, but instead the absence of the obsession to use allows the return of positive character traits that had been pushed aside.  The elimination of negative character traits does not always require rigorous step work— in many cases the negative traits simply disappear as the obsession to use is relieved.&lt;span style=""&gt;  &lt;/span&gt;I base this opinion on my experiences with scores of suboxone patients, and more importantly with the spouses, parents, and children of suboxone patients.&lt;span style=""&gt;  &lt;/span&gt;I have seen multiple instances of improved communication and new-found humility.&lt;span style=""&gt;  &lt;/span&gt;I have heard families talk about ‘having dad back’, and husbands talk about getting back the women they married.&lt;span style=""&gt;  &lt;/span&gt;I sometimes miss my old days as an anesthesiologist placing labor epidurals, as the patients were so grateful—and so I am happy to have found Suboxone treatment, for it is one of the rare areas in psychiatry where patients quickly get better and express gratitude for their care.&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;A natural question is why character defects would simply disappear when the obsession to use is lifted?&lt;span style=""&gt;  &lt;/span&gt;Why wouldn’t it require a great deal of work?&lt;span style=""&gt;  &lt;/span&gt;The answer, I believe, is because the character defects are not the natural personality state of the addict, but rather are traits that are produced by the obsession, and dynamically maintained by the obsession.&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style=";font-size:10;color:black;"  &gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;Combining suboxone treatment and traditional recovery.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;Once the dynamic relationship between use obsession and character defects is understood, the proper relationship between suboxone and traditional recovery becomes clear.&lt;span style=""&gt;  &lt;/span&gt;Should people taking suboxone attend NA or AA?&lt;span style=""&gt;  &lt;/span&gt;Yes, if they want to.&lt;span style=""&gt;  &lt;/span&gt;A 12-step program has much to offer an addict, or anyone for that matter.&lt;span style=""&gt;  &lt;/span&gt;But I see little use in forced or coerced attendance at meetings.&lt;span style=""&gt;  &lt;/span&gt;The recovery message requires a level of acceptance that comes about during desperate times, and people on suboxone do not feel desperate.&lt;span style=""&gt;  &lt;/span&gt;In fact, people on suboxone often report that ‘they feel normal for the first time in their lives’.&lt;span style=""&gt;  &lt;/span&gt;A person in this state of mind is not going to do the difficult personal inventories of AA unless otherwise motivated by his/her own internal desire to change. &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;The role of ‘desperation’ should be addressed at this time:&lt;span style=""&gt;  &lt;/span&gt;In traditional treatment desperation is the most important prerequisite to making progress, as it takes the desperation of being at ‘rock bottom’ to open the mind to see one’s&lt;span style=""&gt;  &lt;/span&gt;powerlessness. But when recovery from addiction is viewed through the remission model, the lack of desperation is a good thing, as it allows the reinstatement of the addict’s own positive character.  Such a view is consistent with the ‘hierarchy of needs’ put forward by Abraham Maslow in 1943; there can be little interest in higher order traits when one is fighting for one’s life. &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;Other Questions (and answers):&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;-Should suboxone patients be in a recovery group?&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;I have similar reservations about forced attendance, but there is something to be gained from the sense of support that a good group can provide.&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;-What is the value of the 4&lt;sup&gt;th&lt;/sup&gt; through 6&lt;sup&gt;th&lt;/sup&gt; steps of a 12-step program, where the addict specifically addresses his/her character defects and asks for their removal by a higher power?&lt;span style=""&gt;  &lt;/span&gt;Are these steps critical to the resolution of character defects?&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;These steps are necessary for addicts in ‘sober recovery’, as the obsession to use will come and go to varying degrees over time depending on the individual and his/her stress level.&lt;span style=""&gt;  &lt;/span&gt;But for a person taking suboxone I see the steps as valuable, but not essential.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;-Where does methadone fit in?&lt;span style=""&gt;  &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;Methadone is just another opiate agonist.&lt;span style=""&gt;  &lt;/span&gt;A newly-raised dosage will prevent cravings temporarily, but as tolerance inevitably rises, cravings will return.&lt;span style=""&gt;  &lt;/span&gt;With cravings comes the obsession to use and the associated character defects.&lt;span style=""&gt;  &lt;/span&gt;This explains the profound difference in the subjective experiences of addicts maintained on suboxone versus methadone, and explains why in my practice I have many patients who have switched to suboxone, but none in the other direction. &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;i style=""&gt;&lt;span style="color:black;"&gt;The downside of suboxone.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/i&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;Practitioners in traditional AODA treatment programs will see suboxone as at best a mixed blessing.&lt;span style=""&gt;  &lt;/span&gt;Desperation is often required to open the addict’s mind to change, and desperation is harder to achieve when an addict has the option to leave treatment and find a practitioner who will prescribe suboxone.&lt;span style=""&gt;  &lt;/span&gt;Suboxone is sometimes used ‘on the street’ by addicts who want to take time off from addiction without committing to long term sobriety.&lt;span style=""&gt;  &lt;/span&gt;Suboxone itself can be abused for short periods of time, until tolerance develops to the drug.&lt;span style=""&gt;  &lt;/span&gt;Snorting suboxone reportedly results in a faster time of onset, without allowing the absorption of the naloxone that prevents intravenous use.&lt;span style=""&gt;  &lt;/span&gt;Finally, the remission model of suboxone use implies long term use of the drug.&lt;span style=""&gt;  &lt;/span&gt;Chronic use of any opiate, including suboxone, has the potential for negative effects on testosterone levels and sexual function, and the use of suboxone is complicated when surgery is necessary. &lt;span style=""&gt; &lt;/span&gt;Short- or moderate-term use of suboxone raises a host of additional questions, including how to convert from drug-induced remission, without desperation, to sober recovery, which often requires desperation.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;The beginning of the future.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;Time will tell whether or not suboxone will work with traditional recovery, or whether there will continue to be two distinct options that are in some ways at odds with each other.  The good news is that treatment of opiate addiction has proven to be profitable for at least one pharmaceutical company, and such success will surely invite a great deal of research into addiction treatment.&lt;span style=""&gt;  &lt;/span&gt;At one time we had two or three treatment options for hypertension, including a drug called reserpine that would never be used for similar indications today.&lt;span style=""&gt;  &lt;/span&gt;Some day we will likely look back on suboxone as the beginning of new age of addiction treatment.&lt;span style=""&gt;  &lt;/span&gt;But for now, the treatment community would be best served by recognizing each other’s strengths, rather than pointing out weaknesses.&lt;/span&gt;&lt;/p&gt;&lt;p class="MsoNormal"&gt;&lt;br /&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;&lt;o:p&gt;&lt;/o:p&gt;This article can be reproduced freely as long as the following attribution is included:&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="color:black;"&gt;The author, Jeffrey T. Junig MD PhD is a psychiatrist in solo practice in Wisconsin, and is Asst Clinical Professor of Psychiatry at the Medical College of Wisconsin.&lt;span style=""&gt;  &lt;/span&gt;Read more articles about suboxone at &lt;a href="http://subox.info/"&gt;http://subox.info&lt;/a&gt; or at Suboxone Talk Zone: &lt;a href="http://subox.info/blog.html"&gt;http://subox.info/blog.html&lt;/a&gt; .&lt;span style=""&gt;  &lt;/span&gt;He can be contacted at &lt;a href="http://fdlpsychiatry.com/"&gt;Fond du Lac Psychiatry&lt;/a&gt; or at the &lt;a href="http://wisconsinopiates.com/"&gt;Wisconsin Opiate Management Center&lt;/a&gt;.  &lt;/span&gt;&lt;span style=";font-size:10;color:black;"  &gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;</description><link>http://subox.info/2008/02/is-suboxone-at-odds-with-traditional.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-6099471916596568039</guid><pubDate>Thu, 31 Jan 2008 04:06:00 +0000</pubDate><atom:updated>2008-01-30T20:27:47.434-08:00</atom:updated><category domain='http://www.blogger.com/atom/ns#'>relapse</category><category domain='http://www.blogger.com/atom/ns#'>recovery</category><category domain='http://www.blogger.com/atom/ns#'>withdrawal</category><title>Question from anonymous</title><description>I am going to move this question to a new post so that everyone can read it:&lt;br /&gt;&lt;p&gt;&lt;br /&gt;&lt;/p&gt;&lt;p&gt;hi jeff-&lt;br /&gt;i am in recoverery and was injured, was on percocets for about three months. i kinds detoxed with a lower dose of opiates but then took a few days worth again after a hard weekend. a few days later the wd symptoms came right back! oh, i couldn't take it so i asked my doctor for suboxone. he knew nothing about it and wanted to give me yet more opiates. after a lot of convincing he gave me 2 mg tabs/30 days worth. I want to be done with all this stuff asap- so what's your suggestion as to how to take this just to make it through the wd's from the opiates? thanks jeff&lt;/p&gt; &lt;p class="comment-timestamp"&gt;January 30, 2008 4:44 AM&lt;/p&gt;&lt;p class="comment-timestamp"&gt;This question illustrates a number of points.  The first point is that opiate addiction is a life-long illness.  Anonymous does not say how long he or she has been 'in recovery', but for the most part it does not matter; people who have been clean for years or even decades will find themselves brought instantly back to the mess they thought they left behind, after just a percocet or two.  As addiction is a conditioned, or learned, process, it makes sense;  If I take you back to your childhood neighborhood after twenty years away, you will likely be able to find your way around without difficulty. Unfortunately we cannot erase conditioned behavior any more than we can intentionally forget bad memories.&lt;/p&gt;&lt;p class="comment-timestamp"&gt;A second point concerns the nature of withdrawal.  I am convinced that the intensity of withdrawal is more related to the intensity of prior withdrawals than to the amount of drug used.  I have heard people describe very severe withdrawal after minimal relapse.  There is a term in medicine-- 'kindling'-- which describes how CNS symptoms such as seizures become worse each time they occur.  I have found that withdrawal is similar.&lt;/p&gt;A third issue is the legality of prescribing opiates.  It is illegal for anyone to prescribe a narcotic for the purpose of avoiding withdrawal, with the exception of certified methadone clinics or suboxone prescribers.  It is illegal for a pain physician to taper a person off opiates to avoid withdrawal; it is illegal for a family practice doc to prescribe vicodin to avoid withdrawal.  A family practice doc can prescribe suboxone for pain, but cannot prescribe suboxone for addiction UNLESS the doc is suboxone certified. &lt;br /&gt;&lt;br /&gt;As for answers, My first question would be, what is/was the nature of your recovery?  If you are involved in AA or NA, I recommend stopping the opiates and getting to a meeting, and then hitting as many meetings as you can for the next few months.  If you hope to be opiate-free again, your best bet is to just stop using, and take the withdrawal. &lt;br /&gt;&lt;br /&gt;If, on the other hand, your recovery was a bit 'shaky', or if you always had intense cravings, or if you just cannot stop using (God forbid that you have found a source of opiates), you may want to consider suboxone.  Many people find that after years of being clean they still felt like an opiate addict just hanging on.... those people will often feel 'normal' for the first time when they take suboxone.  In such a case, though, you would likely end up taking suboxone for a long time-- perhaps for the rest of your life.&lt;br /&gt;&lt;br /&gt;Suboxone can be used to taper off of opiates, but it is most useful in this regard for coming off of high doses of methadone, which is extremely difficult to do.  Suboxone (buprenorphine) is a very potent opiate-- much more potent than oxycodone-- and so it is probably as easy or even easier to come off oxycodone than to come off suboxone.  The problem is that just coming off the opiate, as tough as it seems right now, is really the easy part.  The hard part is staying off of opiates, as you found after your 'tough weekend'.  If you do not have a good program going on in AA or NA, then you really may want to consider suboxone.  It will prevent relapse and put your addiction into remission with a minimum of pain or discomfort.  But again, this is a long term proposition-- just as opiate dependence is a long term illness.</description><link>http://subox.info/2008/01/question-from-anonymous.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-5986267971262440303</guid><pubDate>Fri, 25 Jan 2008 15:34:00 +0000</pubDate><atom:updated>2008-01-25T07:36:52.671-08:00</atom:updated><title>Permissions</title><description>I just changed the settings so that anyone can comment, not just people with gmail accounts.  If you want permission to post NEW topics, send me an e-mail.  I don't need your real name.</description><link>http://subox.info/2008/01/permissions.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-3660408607192026455</guid><pubDate>Wed, 23 Jan 2008 23:17:00 +0000</pubDate><atom:updated>2008-01-23T15:21:48.418-08:00</atom:updated><title>Runny nose, back pain, withdrawal in new patient</title><description>This new patient has been on suboxone for two weeks, and reports having low back pain and a runny nose.  He also feels that the 16 mg dose of suboxone that he takes in the morning wears off by the end of the day.  You can read my answer, and feel free to add your own experiences or suggestions:&lt;br /&gt;&lt;br /&gt; &lt;p class="MsoPlainText"&gt;Hi XXXXXXX,&lt;br /&gt;&lt;/p&gt;    &lt;p class="MsoPlainText"&gt;I received your message.&lt;span style=""&gt;  &lt;/span&gt;A couple thoughts...&lt;span style=""&gt;  &lt;/span&gt;As far as pain goes, the suboxone has the analgesic potency of about 30 mg of methadone or about 50-60 mg of oxycodone.&lt;span style=""&gt;  &lt;/span&gt;Your best bet, with or without suboxone, is to avoid treating back pain with opiates-- that is a dead end street with a pile of messed up lives at the end of it.&lt;span style=""&gt;  &lt;/span&gt;It may be that you were treating aches and pains that you didn't know that you had-- often people on opiates will hurt their backs, knees, whatever, without knowing it, and continue to do more and more damage without the usual warning that our bodies give us (as pain).&lt;span style=""&gt;  &lt;/span&gt;If you try to treat back pain with opiates long term, the tolerance requires higher and higher doses of meds, and the patients gets more and more messed up by the obsession for opiates.&lt;span style=""&gt;  &lt;/span&gt;So...&lt;span style=""&gt;  &lt;/span&gt;the treatment for your back should include 1) rehabilitation either through physical therapy or by your own exercise and stretching routine, 2) anti-inflammatory medication like ibuprofen or naprosyn (over the counter as aleve), 3) avoid re-injury by learning correct lifting technique and avoiding certain things that you know will aggravate it, 4)&lt;span style=""&gt;  &lt;/span&gt;ice after over-use, heat to loosen muscles at night, 5) getting enough sleep, and avoiding things that cause muscle spasm like caffeine, opiates, and alcohol.&lt;/p&gt;    &lt;p class="MsoPlainText"&gt;&lt;o:p&gt; &lt;/o:p&gt;Runny nose... that is sometimes a symptoms of withdrawal.&lt;span style=""&gt;  &lt;/span&gt;That along with your other questions suggests that your tolerance is higher than the opiate effect of suboxone.&lt;span style=""&gt;  &lt;/span&gt;Give it time, and it will go away-- if it is still there after a couple weeks I would start to think it is something else, like a virus.&lt;/p&gt;    &lt;p class="MsoPlainText"&gt;&lt;o:p&gt; &lt;/o:p&gt;As far as the meds 'wearing off', I have had the benefit of seeing the pharmacologic data on the drug buprenorphine when I was doing my 'treatment advocate' training with the company.&lt;span style=""&gt;  &lt;/span&gt;The drug lasts forever in us humans-- when a person stops taking subox the 'real withdrawal' doesn't hit for 3-5 days.&lt;span style=""&gt;  &lt;/span&gt;In your case, you are likely feeling a combination of things.&lt;span style=""&gt;  &lt;/span&gt;First, as I said in the prior paragraph, you are having mild withdrawal from 'mismatch' between your tolerance and the suboxone-- this will resolve soon.&lt;span style=""&gt;  &lt;/span&gt;Second, it is not uncommon for people to have full- blown withdrawal symptoms that come from our brains 'replaying' our earlier withdrawals.&lt;span style=""&gt;  &lt;/span&gt;Usually the more we focus on them, the worse they become.&lt;span style=""&gt;  &lt;/span&gt;They will fade away as your tolerance adjusts-- by the time I see you again they should be gone.&lt;span style=""&gt;  &lt;/span&gt;In the meantime try to keep busy and distract yourself as soon as you sense them coming, or if they come at a certain time each day try to keep busy at that time.&lt;span style=""&gt;  &lt;/span&gt;More subox will not help, because of the ceiling effect of the drug-- your receptors are all bound up at 8-16 mg/day.&lt;/p&gt;    &lt;p class="MsoPlainText"&gt;Call Nancy to set up an appointment soon, because we do fill up!&lt;/p&gt;    &lt;p class="MsoPlainText"&gt;&lt;o:p&gt; &lt;/o:p&gt;Take care,&lt;/p&gt;  J</description><link>http://subox.info/2008/01/runny-nose-back-pain-withdrawal-in-new.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-8076435562291716925</guid><pubDate>Wed, 23 Jan 2008 23:16:00 +0000</pubDate><atom:updated>2008-01-23T15:16:57.679-08:00</atom:updated><title>C'Mon-- Write Back!</title><description>Feel free to hit the 'comments' button to post follow-up questions to any post!</description><link>http://subox.info/2008/01/cmon-write-back.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-6238108876175175728</guid><pubDate>Wed, 23 Jan 2008 22:50:00 +0000</pubDate><atom:updated>2008-01-23T14:53:11.544-08:00</atom:updated><title>New patient having nausea</title><description>Nausea is not uncommon in patients starting suboxone.  Please read what I wrote to this patient:&lt;br /&gt;&lt;br /&gt;Nausea usually comes about if the opiate effect of the suboxone is stronger than what you were used to.  Reduce the dose to half a pill per day-- that will be enough to prevent withdrawal (even a quarter of a pill per day will prevent withdrawal), but hopefully won't be so much that you get sick.  Once you tolerate that dose, you can slowly increase every few days to the full amount.&lt;br /&gt; &lt;br /&gt;Sometimes the nausea comes from the naloxone, and we have to go with subutex-- but subutex is more expensive and less available.  Usually reducing the dose does the trick.  The nausea is almost always gone after 4-5 days.  I could prescribe a med to reduce nausea-- send me the phone number of a pharmacy if you want me to call in compazine.  That med will make you sleepy, though, and has other potential side effects.  For example, it can make your muscles twitch without your ability to control them (the symptoms go away after the drug wears off, in about 6 hours).&lt;br /&gt;&lt;br /&gt;Again, send me a pharmacy phone number if you like, or otherwise give it a couple days at the reduced dose.&lt;br /&gt;&lt;br /&gt;J</description><link>http://subox.info/2008/01/new-patient-having-nausea.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-6484155917114848249</guid><pubDate>Sun, 20 Jan 2008 22:47:00 +0000</pubDate><atom:updated>2008-01-20T15:00:52.375-08:00</atom:updated><title>Here's an idea...</title><description>I know from my radio show that I will need to talk by myself for awhile...  I often get letters from patients that ask specific questions that can be answered in general ways.  I will include my responses, blocking any personal information, and maybe others will read my opinions and learn from them.  Today I received an e-mail from a patient complaining that she takes one 8 mg dose in the AM, and by noon she thinks it has worn off.  She uses the suboxone for pain control; before suboxone she was a bit out of control with narcotic pain pills--we all know how it goes-- running out early and withdrawing, or always needing more, or fearing that her lecturing doc would stop prescribing.  Hear is my response:&lt;br /&gt;&lt;br /&gt;Dear XXXX,&lt;br /&gt;&lt;br /&gt;Yes, I did receive your message.  Clarify for me a couple things—when you say ‘by mid day you feel the same’ I’m not sure what you mean.  Feel the same to when? To before you took the dose?  And what feelings are you talking about—pain? Or withdrawal?&lt;br /&gt;&lt;br /&gt;Every day, another study comes out looking at the unique way that buprenorphine acts in the body (buprenorphine is the active substance in suboxone).  We now know that the action of buprenorphine at different doses can be plotted out to form a bell-shaped curve.  To visualize how this works, picture the liberty bell sitting on the ‘x’ (flat) axis, and the outline of the bell represents the opiate effect of the drug, as the dose is increased going from left to right.  To translate what that mean for the patient, the effect increases as the dose goes up to 2 mg, and then levels out for awhile (the bell has a wide, flat top).  Then at high doses the drug blocks itself, and the activity decreases again.  In a patient, that means that you will get some pain control out of the drug up to about 2 mg per day, but then higher doses have no significantly higher effect.  At much higher doses the drug actually blocks its own opiate activity and causes withdrawal.&lt;br /&gt;&lt;br /&gt;The other thing we know is that the drug is extremely long acting.  A single 8 mg dose will prevent withdrawal for 3-4 days.  I can be certain that when you take 4 or 8 mg, the level of drug in your system will be virtually constant for 24 hours.  The fact that you feel less after such a short period of time suggests that other factors are at play—the psychological effects of opiates in opiate users is almost as strong sometimes as the effects of the drugs themselves.  I have noted that my patients' reactions are consistent with the pharmacodynamics of buprenorphine.  For example, people who taper off suboxone find that it is very easy to go from 16 or 24 mg per day down to 4 mg per day—there is no significant withdrawal for that move.  But going down that last bit, below 2-4 mg, causes withdrawal.&lt;br /&gt;&lt;br /&gt;For you, you will not get any increase in pain control at higher doses.  In fact, if you took doses higher than 32 mg you may start to get less pain control as the drug blocks itself.  Likewise, increasing the dose from 8 to 16 mg will not make it last any longer, as it is already lasting several days.  I can easily prove that to you—just stop taking the drug, and you will find that on day 3 or day 4 you will have withdrawal as it finally leaves your body.  The main benefit from raising from 8 to 16 mg is the drop in cravings at the higher dose.&lt;br /&gt;&lt;br /&gt;In your case, there is certainly a strong element of relief that is connected to just taking a pill.  I would have no problem increasing you to 16 mg per day, but it would cost more, and I doubt it will reduce pain much more effectively.  There are some points that are important for you to remember:  &lt;br /&gt;&lt;br /&gt;Opiate users derive a certain comfort from the drama of taking substances.  I don’t know if it is the distraction, the placebo effect, or the feeling of being more in control from taking a medication.  This 'comfort' sometimes becomes important enough that the patient thinks it is something they really need. But be aware of the limitations of the medication.  For chronic pain, there never is a magic bullet that will do all that we need it to do. We have meds that can take the edge off of discomfort, but most of the improvement in function will come from non-med sources.&lt;br /&gt;&lt;br /&gt;Examples of non-med sources include first and foremost, exercise.  Low grade exercise, and just as importantly gentle stretching, are the primary healing function for fibromyalgia and other chronic pain conditions.  Without exercise and stretching, the patient will not improve, and if on narcotics will likely do worse over time.&lt;br /&gt;&lt;br /&gt;Ibuprofen and Tylenol are often helpful adjuncts to narcotics, and are not a problem when taking suboxone.&lt;br /&gt;&lt;br /&gt;It is common for patients who have taken higher amounts of opiates to become quite focused on the effects of the drug.  A person without addiction will take a pain pill for pain, and the resume activity without a second thought about the medication.  At the end of the day he/she is likely hard pressed to remember if or when the med stopped working.  People used to taking opiates are hyperaware of when the drug sets in, when it levels out, and when it decreases.  They lose the opportunity to find pleasure in whatever it was that they were going to do on that particular day, because the whole day becomes about the medication.  Ideally, suboxone will allow the patient to confidently know that the med is working, and that it will last all day—so there is no need to think about it and wait for it to wear off.  Try to see the way that opiates grab your attention, and try to distract yourself by taking up some other activity that interest you or that you enjoy.  Pain is always at its worst when one is highlighting it with attention.&lt;br /&gt;&lt;br /&gt;Anwer my questions when you get a chance.  Let me know if you think 16 mg will be helpful, as maybe you are craving opiates a bit.  Finally, make sure that you are putting time aside for stretching and exercise—at least an hour or two per day.  &lt;br /&gt;&lt;br /&gt;JJ&lt;br /&gt;&lt;br /&gt;I'm off to watch some football.  Go Pack!!  Oh-- and please, don't be shy. Add your questions or comments.</description><link>http://subox.info/2008/01/heres-idea.html</link><author>Jeffrey Junig</author></item><item><guid isPermaLink='false'>tag:blogger.com,1999:blog-4472611192504114204.post-5758004385102432329</guid><pubDate>Sat, 19 Jan 2008 02:42:00 +0000</pubDate><atom:updated>2008-01-18T18:58:37.454-08:00</atom:updated><category domain='http://www.blogger.com/atom/ns#'>suboxone</category><category domain='http://www.blogger.com/atom/ns#'>buprenorphine</category><category domain='http://www.blogger.com/atom/ns#'>addiction</category><category domain='http://www.blogger.com/atom/ns#'>withdrawal</category><category domain='http://www.blogger.com/atom/ns#'>pain pill</category><category domain='http://www.blogger.com/atom/ns#'>opiate</category><category domain='http://www.blogger.com/atom/ns#'>methadone</category><title>Let's Talk</title><description>One of the comments I hear the most from suboxone piatients that they had their own group-- a place to talk about addiction issues, frustrations, inspirations, etc, without the need to hide their use of suboxone. Many suboxone patients attend AA or NA for the fellowship, but are held back from complete honesty for fear of being ostracized (a valid fear).&lt;br /&gt;&lt;br /&gt;My hope is that suboxone patients will use this site to discuss their experiences, hopes, and frustrations in a positive way. This is not a forum to debate whether or not suboxone is a wonder drug or the work of the devil, as there are already plenty of sites dedicated to particularly the latter opinion. But for those patients who are taking suboxone to induce remission of opiate addiction, who prefer the stability and normal mind that comes from suboxone maintenance over the chains of active opiate addiction, please use this space to tell your story, to ask questions, to post answers, or to just say 'hello'.&lt;br /&gt;&lt;br /&gt;To comment on a topic, click on the word 'comments'. At the present time I do not plan to moderate what is written. If you would like to author your own articles or topics, send me an e-mail at blog@subox.info and I will give you permission.</description><link>http://subox.info/2008/01/lets-talk.html</link><author>Jeffrey Junig</author></item></channel></rss>